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Trade-offs between tRNA abundance and mRNA secondary structure support smoothing of translation elongation rate

Translation of protein from mRNA is a complex multi-step process that occurs at a non-uniform rate. Variability in ribosome speed along an mRNA enables refinement of the proteome and plays a critical role in protein biogenesis. Detailed single protein studies have found both tRNA abundance and mRNA...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Gorochowski, Thomas E., Ignatova, Zoya, Bovenberg, Roel A.L., Roubos, Johannes A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381083/
https://ncbi.nlm.nih.gov/pubmed/25765653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv199
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