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Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G

During protein synthesis, elongation of the polypeptide chain by each amino acid is followed by a translocation step in which mRNA and transfer RNA (tRNA) are advanced by one codon. This crucial step is catalyzed by elongation factor G (EF-G), a guanosine triphosphatase (GTPase), and accompanied by...

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Détails bibliographiques
Publié dans:Sci Adv
Auteurs principaux: Li, Wen, Liu, Zheng, Koripella, Ravi Kiran, Langlois, Robert, Sanyal, Suparna, Frank, Joachim
Format: Artigo
Langue:Inglês
Publié: American Association for the Advancement of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517844/
https://ncbi.nlm.nih.gov/pubmed/26229983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500169
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