Φορτώνει......
Systematic analysis of BRAF(V)(600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis
Drugs that inhibit RAF/MEK signaling, such as vemurafenib, elicit profound but often temporary anti-tumor responses in patients with BRAF(V)(600E) melanoma. Adaptive responses to RAF/MEK inhibition occur on a timescale of hours to days, involve homeostatic responses that reactivate MAP kinase signal...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Syst Biol |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BlackWell Publishing Ltd
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4380931/ https://ncbi.nlm.nih.gov/pubmed/25814555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20145877 |
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