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The fitness costs of antibiotic resistance mutations

Antibiotic resistance is increasing in pathogenic microbial populations and is thus a major threat to public health. The fate of a resistance mutation in pathogen populations is determined in part by its fitness. Mutations that suffer little or no fitness cost are more likely to persist in the absen...

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Bibliographic Details
Published in:Evol Appl
Main Authors: Melnyk, Anita H, Wong, Alex, Kassen, Rees
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380921/
https://ncbi.nlm.nih.gov/pubmed/25861385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/eva.12196
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