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Compensation of Fitness Costs and Reversibility of Antibiotic Resistance Mutations

Strains of bacterial pathogens that have acquired mutations conferring antibiotic resistance often have a lower growth rate and are less invasive or transmissible initially than their susceptible counterparts. However, fitness costs of resistance mutations can be ameliorated by secondary site mutati...

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Detalhes bibliográficos
Main Authors: Schulz zur Wiesch, Pia, Engelstädter, Jan, Bonhoeffer, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863634/
https://ncbi.nlm.nih.gov/pubmed/20176903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01460-09
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