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Compensating the Fitness Costs of Synonymous Mutations

Synonymous mutations do not change the sequence of the polypeptide but they may still influence fitness. We investigated in Salmonella enterica how four synonymous mutations in the rpsT gene (encoding ribosomal protein S20) reduce fitness (i.e., growth rate) and the mechanisms by which this cost can...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Knöppel, Anna, Näsvall, Joakim, Andersson, Dan I.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868123/
https://ncbi.nlm.nih.gov/pubmed/26882986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msw028
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