Fitness Costs of Drug Resistance Mutations in Multidrug-Resistant Mycobacterium tuberculosis: A Household-Based Case-Control Study

BACKGROUND: The projected long-term prevalence of multidrug-resistant (MDR) tuberculosis depends upon the relative fitness of MDR Mycobacterium tuberculosis strains, compared with non-MDR strains. While many experimental models have tested the in vitro or in vivo fitness costs of various drug resist...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Salvatore, Phillip P., Becerra, Mercedes C., Abel zur Wiesch, Pia, Hinkley, Trevor, Kaur, Devinder, Sloutsky, Alexander, Cohen, Ted
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676541/
https://ncbi.nlm.nih.gov/pubmed/26092854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv347
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