Error-prone initiation factor 2 mutations reduce the fitness cost of antibiotic resistance

Mutations in the fmt gene (encoding formyl methionine transferase) that eliminate formylation of initiator tRNA (Met-tRNA(i)) confer resistance to the novel antibiotic class of peptide deformylase inhibitors (PDFIs) while concomitantly reducing bacterial fitness. Here we show in Salmonella typhimuri...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Zorzet, Anna, Pavlov, Michael Y, Nilsson, Annika I, Ehrenberg, Måns, Andersson, Dan I
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2010
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859245/
https://ncbi.nlm.nih.gov/pubmed/20132454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2010.07057.x
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares