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Evolution of Cost-Free Resistance under Fluctuating Drug Selection in Pseudomonas aeruginosa

Antibiotic resistance evolves rapidly in response to drug selection, but it can also persist at appreciable levels even after the removal of the antibiotic. This suggests that many resistant strains can both be resistant and have high fitness in the absence of antibiotics. To explore the conditions...

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Bibliographic Details
Published in:mSphere
Main Authors: Melnyk, Anita H., McCloskey, Nicholas, Hinz, Aaron J., Dettman, Jeremy, Kassen, Rees
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518267/
https://ncbi.nlm.nih.gov/pubmed/28744479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00158-17
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