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Detergent-solubilized Patched Purified from Sf9 Cells Fails to Interact Strongly With Cognate Hedgehog or Ihog Homologs
Patched (Ptc) is a twelve-pass transmembrane protein that functions as a receptor for the Hedgehog (Hh) family of morphogens. In addition to Ptc, several accessory proteins including the CDO/Ihog family of co-receptors are necessary for proper Hh signaling. Structures of Hh proteins bound to members...
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| Udgivet i: | Protein Expr Purif |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4380871/ https://ncbi.nlm.nih.gov/pubmed/25261717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2014.09.012 |
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