Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form

Transferrin receptor-2 is a transmembrane protein whose expression is restricted to hepatocytes and erythroid cells. Transferrin receptor-2 has a regulatory function in iron homeostasis, since its inactivation causes systemic iron overload. Hepatic transferrin receptor-2 participates in iron sensing...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Haematologica
Prif Awduron: Pagani, Alessia, Vieillevoye, Maud, Nai, Antonella, Rausa, Marco, Ladli, Meriem, Lacombe, Catherine, Mayeux, Patrick, Verdier, Frédérique, Camaschella, Clara, Silvestri, Laura
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ferrata Storti Foundation 2015
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380718/
https://ncbi.nlm.nih.gov/pubmed/25637053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.118521
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