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The extrahepatic role of TFR2 in iron homeostasis

Transferrin receptor 2 (TFR2), a protein homologous to the cell iron importer TFR1, is expressed in the liver and erythroid cells and is reported to bind diferric transferrin, although at lower affinity than TFR1. TFR2 gene is mutated in type 3 hemochromatosis, a disorder characterized by iron overl...

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Bibliografische gegevens
Hoofdauteurs: Silvestri, Laura, Nai, Antonella, Pagani, Alessia, Camaschella, Clara
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019842/
https://ncbi.nlm.nih.gov/pubmed/24847265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00093
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