Identification of TMPRSS6 cleavage sites of hemojuvelin

Hemojuvelin (HJV), the coreceptor of the BMP-SMAD pathway that up-regulates hepcidin transcription, is a repulsive guidance molecule (RGMc) which undergoes a complex intracellular processing. Following autoproteolysis, it is exported to the cell surface both as a full-length and a heterodimeric prot...

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Publicat a:J Cell Mol Med
Autors principals: Rausa, Marco, Ghitti, Michela, Pagani, Alessia, Nai, Antonella, Campanella, Alessandro, Musco, Giovanna, Camaschella, Clara, Silvestri, Laura
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395201/
https://ncbi.nlm.nih.gov/pubmed/25704252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12462
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