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TLR7, IFNγ, and T-bet: their roles in the development of ABCs in female-biased autoimmunity

The majority of autoimmune diseases have a strong gender bias, affecting mostly females. Gender-specific factors like sex-hormones, the presence or absence of a second X chromosome, and gender-specific gut microbiota may contribute to this bias. In this review we will discuss the role of the X chrom...

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Detalhes bibliográficos
Publicado no:Cell Immunol
Main Authors: Rubtsova, Kira, Marrack, Philippa, Rubtsov, Anatoly V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380581/
https://ncbi.nlm.nih.gov/pubmed/25541140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2014.12.002
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