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Age-associated B cells: A T-bet dependent effector with roles in protective and pathogenic immunity

A newly discovered B cell subset, Age Associated B Cells, expresses the transcription factor T-bet, has a unique surface phenotype, and progressively accumulates with age. Moreover, B cells with these general features are associated with viral infections and autoimmunity in both mice and humans. Her...

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Pubblicato in:J Immunol
Autori principali: Rubtsova, Kira, Rubtsov, Anatoly V., Cancro, Michael P., Marrack, Philippa
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548292/
https://ncbi.nlm.nih.gov/pubmed/26297793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501209
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