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Tyrosine phosphatase PTPα regulates focal adhesion remodeling through Rac1 activation
We characterized the role of protein tyrosine phosphatase (PTP)-α in focal adhesion (FA) formation and remodeling using wild-type and PTPα-deficient (PTPα(−/−)) cells. Compared with wild-type cells, spreading PTPα(−/−) fibroblasts displayed fewer leading edges and formed elongated α-actinin-enriched...
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| Yayımlandı: | Am J Physiol Cell Physiol |
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| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Physiological Society
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4380481/ https://ncbi.nlm.nih.gov/pubmed/18216165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00359.2007 |
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