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B cell antigen presentation in the initiation of Follicular Helper T cell and Germinal Center differentiation

High affinity class-switched antibodies and memory B cells are products of the germinal center. The CD4(+) T cell help required for the development and maintenance of the germinal center is delivered by follicular helper T cells (T(FH)), a CD4(+) helper T cell subset characterized by expression of B...

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Barnett, Lisa G., Simkins, Helen M.A., Barnett, Burton E., Korn, Lisa L., Johnson, Andy L., Wherry, E. John, Wu, Gregory F., Laufer, Terri M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380085/
https://ncbi.nlm.nih.gov/pubmed/24646739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301284
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