Toll-like receptor 4 ablation in mdx mice reveals innate immunity as a therapeutic target in Duchenne muscular dystrophy

Toll-like receptor 4 (TLR4) recognizes specific structural motifs associated with microbial pathogens and also responds to certain endogenous host molecules associated with tissue damage. In Duchenne muscular dystrophy (DMD), inflammation plays an important role in determining the ultimate fate of d...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Giordano, Christian, Mojumdar, Kamalika, Liang, Feng, Lemaire, Christian, Li, Tong, Richardson, John, Divangahi, Maziar, Qureshi, Salman, Petrof, Basil J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380065/
https://ncbi.nlm.nih.gov/pubmed/25552658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu735
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