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Toll-like receptor 4 ablation in mdx mice reveals innate immunity as a therapeutic target in Duchenne muscular dystrophy

Toll-like receptor 4 (TLR4) recognizes specific structural motifs associated with microbial pathogens and also responds to certain endogenous host molecules associated with tissue damage. In Duchenne muscular dystrophy (DMD), inflammation plays an important role in determining the ultimate fate of d...

詳細記述

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書誌詳細
出版年:Hum Mol Genet
主要な著者: Giordano, Christian, Mojumdar, Kamalika, Liang, Feng, Lemaire, Christian, Li, Tong, Richardson, John, Divangahi, Maziar, Qureshi, Salman, Petrof, Basil J.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380065/
https://ncbi.nlm.nih.gov/pubmed/25552658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu735
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