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The dual CCR2/CCR5 chemokine receptor antagonist Cenicriviroc reduces macrophage infiltration and disease severity in Duchenne muscular dystrophy (Dmd(mdx-4Cv)) mice

Duchenne muscular dystrophy (DMD) is characterized by progressive muscle weakness which is ultimately fatal, most often due to involvement of the diaphragm. Macrophage infiltration of dystrophic muscles has been strongly linked to muscle damage and fibrosis in DMD. We hypothesized that cenicriviroc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liang, Feng, Giordano, Christian, Shang, Dong, Li, Qian, Petrof, Basil J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862483/
https://ncbi.nlm.nih.gov/pubmed/29561896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194421
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