Human pluripotent stem cell derived midbrain PITX3(eGFP/w) neurons: a versatile tool for pharmacological screening and neurodegenerative modeling

PITX3 expression is confined to adult midbrain dopaminergic (mDA) neurons. In this study we describe the generation and basic functional characteristics of mDA neurons derived from a human pluripotent stem cell (hPSC) line expressing eGFP under the control of the PITX3 promoter. Flow cytometry showe...

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Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Watmuff, Bradley, Hartley, Brigham J., Hunt, Cameron P. J., Fabb, Stewart A., Pouton, Colin W., Haynes, John M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379917/
https://ncbi.nlm.nih.gov/pubmed/25873861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00104
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