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Human pluripotent stem cell derived midbrain PITX3(eGFP/w) neurons: a versatile tool for pharmacological screening and neurodegenerative modeling

PITX3 expression is confined to adult midbrain dopaminergic (mDA) neurons. In this study we describe the generation and basic functional characteristics of mDA neurons derived from a human pluripotent stem cell (hPSC) line expressing eGFP under the control of the PITX3 promoter. Flow cytometry showe...

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Pubblicato in:Front Cell Neurosci
Autori principali: Watmuff, Bradley, Hartley, Brigham J., Hunt, Cameron P. J., Fabb, Stewart A., Pouton, Colin W., Haynes, John M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379917/
https://ncbi.nlm.nih.gov/pubmed/25873861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00104
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