Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology

Neurofibrillary tangles (NFTs) are composed of abnormal aggregates of the cytoskeletal protein tau. Together with amyloid β (Aβ) plaques and neuronal and synaptic loss, NFTs constitute the primary pathological hallmarks of Alzheimer disease (AD). Recent evidence also suggests that caspases are activ...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Rissman, Robert A., Poon, Wayne W., Blurton-Jones, Mathew, Oddo, Salvatore, Torp, Reidun, Vitek, Michael P., LaFerla, Frank M., Rohn, Troy T., Cotman, Carl W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2004
Fag:
Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC437967/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15232619/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI20640
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker