Tolerance induced by inhaled antigen involves CD4(+) T cells expressing membrane-bound TGF-β and FOXP3

Under normal circumstances, the respiratory tract maintains immune tolerance in the face of constant antigen provocation. Using a murine model of tolerance induced by repeated exposure to a low dose of aerosolized antigen, we show an important contribution by CD4(+) T cells in the establishment and...

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Autores principales: Ostroukhova, Marina, Seguin-Devaux, Carole, Oriss, Timothy B., Dixon-McCarthy, Barbara, Yang, Liyan, Ameredes, Bill T., Corcoran, Timothy E., Ray, Anuradha
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2004
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC437966/
https://ncbi.nlm.nih.gov/pubmed/15232609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420509
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