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Foxp3-independent mechanism by which TGF-β controls peripheral T cell tolerance

Peripheral T cell tolerance is promoted by the regulatory cytokine TGF-β and Foxp3-expressing Treg cells. However, whether TGF-β and Treg cells are part of the same regulatory module, or exist largely as distinct pathways to repress self-reactive T cells remains incompletely understood. Using a tran...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Oh, Soyoung A., Liu, Ming, Nixon, Briana G., Kang, Davina, Toure, Ahmed, Bivona, Michael, Li, Ming O.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5594672/
https://ncbi.nlm.nih.gov/pubmed/28827353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706356114
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