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HPV-E7 Delivered by Engineered Exosomes Elicits a Protective CD8(+) T Cell-Mediated Immune Response

We developed an innovative strategy to induce a cytotoxic T cell (CTL) immune response against protein antigens of choice. It relies on the production of exosomes, i.e., nanovesicles spontaneously released by all cell types. We engineered the upload of huge amounts of protein antigens upon fusion wi...

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Библиографические подробности
Опубликовано в: :Viruses
Главные авторы: Di Bonito, Paola, Ridolfi, Barbara, Columba-Cabezas, Sandra, Giovannelli, Andrea, Chiozzini, Chiara, Manfredi, Francesco, Anticoli, Simona, Arenaccio, Claudia, Federico, Maurizio
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379561/
https://ncbi.nlm.nih.gov/pubmed/25760140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7031079
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