HPV-E7 Delivered by Engineered Exosomes Elicits a Protective CD8(+) T Cell-Mediated Immune Response

We developed an innovative strategy to induce a cytotoxic T cell (CTL) immune response against protein antigens of choice. It relies on the production of exosomes, i.e., nanovesicles spontaneously released by all cell types. We engineered the upload of huge amounts of protein antigens upon fusion wi...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Di Bonito, Paola, Ridolfi, Barbara, Columba-Cabezas, Sandra, Giovannelli, Andrea, Chiozzini, Chiara, Manfredi, Francesco, Anticoli, Simona, Arenaccio, Claudia, Federico, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379561/
https://ncbi.nlm.nih.gov/pubmed/25760140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7031079
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