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Exosomes from Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Cells License Quiescent CD4(+) T Lymphocytes To Replicate HIV-1 through a Nef- and ADAM17-Dependent Mechanism
Resting CD4(+) T lymphocytes resist human immunodeficiency virus (HIV) infection. Here, we provide evidence that exosomes from HIV-1-infected cells render resting human primary CD4(+) T lymphocytes permissive to HIV-1 replication. These results were obtained with transwell cocultures of HIV-1-infect...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Microbiology
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4178784/ https://ncbi.nlm.nih.gov/pubmed/25056899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01712-14 |
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