Cell activation and HIV-1 replication in unstimulated CD4(+) T lymphocytes ingesting exosomes from cells expressing defective HIV-1

BACKGROUND: A relevant burden of defective HIV-1 genomes populates PBMCs from HIV-1 infected patients, especially during HAART treatment. These viral genomes, although unable to codify for infectious viral particles, can express viral proteins which may affect functions of host cells as well as byst...

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Vydáno v:Retrovirology
Hlavní autoři: Arenaccio, Claudia, Chiozzini, Chiara, Columba-Cabezas, Sandra, Manfredi, Francesco, Federico, Maurizio
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229896/
https://ncbi.nlm.nih.gov/pubmed/24924541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-11-46
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