Cell activation and HIV-1 replication in unstimulated CD4(+) T lymphocytes ingesting exosomes from cells expressing defective HIV-1

BACKGROUND: A relevant burden of defective HIV-1 genomes populates PBMCs from HIV-1 infected patients, especially during HAART treatment. These viral genomes, although unable to codify for infectious viral particles, can express viral proteins which may affect functions of host cells as well as byst...

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Bibliographic Details
Published in:Retrovirology
Main Authors: Arenaccio, Claudia, Chiozzini, Chiara, Columba-Cabezas, Sandra, Manfredi, Francesco, Federico, Maurizio
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229896/
https://ncbi.nlm.nih.gov/pubmed/24924541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-11-46
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