Cryptococcus neoformans-induced macrophage lysosome damage crucially contributes to fungal virulence()

Upon ingestion by macrophages, Cryptococcus neoformans (Cn) can survive and replicate intracellularly unless the macrophages become classically activated. The mechanism enabling intracellular replication is not fully understood; neither are the mechanisms which allow classical activation to countera...

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Vydáno v:J Immunol
Hlavní autoři: Davis, Michael J., Eastman, Alison J., Qiu, Yafeng, Gregorka, Brian, Kozel, Thomas R., Osterholzer, John J., Curtis, Jeffrey L., Swanson, Joel A., Olszewski, Michal A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379045/
https://ncbi.nlm.nih.gov/pubmed/25637026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402376
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