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Cryptococcus neoformans-induced macrophage lysosome damage crucially contributes to fungal virulence()

Upon ingestion by macrophages, Cryptococcus neoformans (Cn) can survive and replicate intracellularly unless the macrophages become classically activated. The mechanism enabling intracellular replication is not fully understood; neither are the mechanisms which allow classical activation to countera...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Davis, Michael J., Eastman, Alison J., Qiu, Yafeng, Gregorka, Brian, Kozel, Thomas R., Osterholzer, John J., Curtis, Jeffrey L., Swanson, Joel A., Olszewski, Michal A.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379045/
https://ncbi.nlm.nih.gov/pubmed/25637026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402376
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