Cryptococcus neoformans copper detoxification machinery is critical for fungal virulence

Copper (Cu) is an essential metal that is toxic at high concentrations. Thus, pathogens often rely on host Cu for growth, but host cells can hyper-accumulate Cu to exert anti-microbial effects. The human fungal pathogen Cryptococcus neoformans encodes various Cu-responsive genes but their role in in...

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Main Authors: Ding, Chen, Festa, Richard A., Chen, Ying-Lien, Espart, Anna, Palacios, Òscar, Espín, Jordi, Capdevila, Mercè, Atrian, Sílvia, Heitman, Joseph, Thiele, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668348/
https://ncbi.nlm.nih.gov/pubmed/23498952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.02.002
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