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Cryptococcus neoformans Iron-Sulfur Protein Biogenesis Machinery Is a Novel Layer of Protection against Cu Stress

Copper (Cu) ions serve as catalytic cofactors to drive key biochemical processes, and yet Cu levels that exceed cellular homeostatic control capacity are toxic. The underlying mechanisms for Cu toxicity are poorly understood. During pulmonary infection by the fungal pathogen Cryptococcus neoformans,...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Garcia-Santamarina, Sarela, Uzarska, Marta A., Festa, Richard A., Lill, Roland, Thiele, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666163/
https://ncbi.nlm.nih.gov/pubmed/29089435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01742-17
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