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Cryptococcus neoformans copper detoxification machinery is critical for fungal virulence

Copper (Cu) is an essential metal that is toxic at high concentrations. Thus, pathogens often rely on host Cu for growth, but host cells can hyper-accumulate Cu to exert anti-microbial effects. The human fungal pathogen Cryptococcus neoformans encodes various Cu-responsive genes but their role in in...

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Détails bibliographiques
Auteurs principaux: Ding, Chen, Festa, Richard A., Chen, Ying-Lien, Espart, Anna, Palacios, Òscar, Espín, Jordi, Capdevila, Mercè, Atrian, Sílvia, Heitman, Joseph, Thiele, Dennis J.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668348/
https://ncbi.nlm.nih.gov/pubmed/23498952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.02.002
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