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Compartmentalization of a bistable switch enables memory to cross a feedback-driven transition

Cells make accurate decisions in the face of molecular noise and environmental fluctuations by relying not only on present pathway activity, but also on their memory of past signaling dynamics. Once a decision is made, cellular transitions are often rapid and switch-like due to positive feedback loo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell
Prif Awduron: Doncic, Andreas, Atay, Oguzhan, Valk, Ervin, Grande, Alicia, Bush, Alan, Vasen, Gustavo, Colman-Lerner, Alejandro, Loog, Mart, Skotheim, Jan M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377233/
https://ncbi.nlm.nih.gov/pubmed/25768911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.02.032
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