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Compartmentalization of a bistable switch enables memory to cross a feedback-driven transition
Cells make accurate decisions in the face of molecular noise and environmental fluctuations by relying not only on present pathway activity, but also on their memory of past signaling dynamics. Once a decision is made, cellular transitions are often rapid and switch-like due to positive feedback loo...
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Publicado no: | Cell |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4377233/ https://ncbi.nlm.nih.gov/pubmed/25768911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.02.032 |
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