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Targeting Multiple Key Signaling Pathways in Melanoma using Leelamine

Melanoma is a highly drug resistant cancer with resistance developing to agents targeting single proteins. To circumvent this problem, a new class of agent inhibiting multiple key pathways important in this disease is being developed to reduce the likelihood of developing resistant disease. The PI3...

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Bibliographic Details
Published in:Mol Cancer Ther
Main Authors: Gowda, Raghavendra, Madhunapantula, SubbaRao V., Kuzu, Omer F., Sharma, Arati, Robertson, Gavin P.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377161/
https://ncbi.nlm.nih.gov/pubmed/24688050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0867
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