Dissociation of mu opioid receptor and CRF-R1 antagonist effects on escalated ethanol consumption and mPFC serotonin in C57BL/6J mice

Both the opioid antagonist naltrexone and corticotropin-releasing factor type-1 receptor (CRF-R1) antagonists have been investigated for the treatment of alcoholism. The current study examines the combination of naltrexone and CP154526 to reduce intermittent access ethanol drinking (IAA) in C57BL/6J...

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Vydáno v:Addict Biol
Hlavní autoři: Hwa, Lara S., Shimamoto, Akiko, Kayyali, Tala, Norman, Kevin J., Valentino, Rita J., DeBold, Joseph F., Miczek, Klaus A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377124/
https://ncbi.nlm.nih.gov/pubmed/25262980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12189
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