Aggression and increased glutamate in the mPFC during withdrawal from intermittent alcohol in outbred mice

RATIONALE: Disrupted social behavior, including occasional aggressive outbursts, is characteristic of withdrawal from long-term alcohol (EtOH) use. Heavy EtOH use and exaggerated responses during withdrawal may be treated using glutamatergic N-methyl-D-aspartate receptor (NMDAR) antagonists. OBJECTI...

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Publicado no:Psychopharmacology (Berl)
Main Authors: Hwa, Lara S., Nathanson, Anna J., Shimamoto, Akiko, Tayeh, Jillian K., Wilens, Allison R., Holly, Elizabeth N., Newman, Emily L., DeBold, Joseph F., Miczek, Klaus A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515187/
https://ncbi.nlm.nih.gov/pubmed/25899790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-015-3925-y
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