Prevention of Alcohol-Heightened Aggression by CRF-R1 Antagonists in Mice: Critical Role for DRN-PFC Serotonin Pathway

Alcohol can escalate aggressive behavior in a significant subgroup of rodents, humans, and nonhuman primates. The present study investigated whether blockade of corticotropin-releasing factor receptor type 1 (CRF-R1) could prevent the emergence of alcohol-heightened aggression in mice. The serotonin...

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Autors principals: Quadros, Isabel M, Hwa, Lara S, Shimamoto, Akiko, Carlson, Julia, DeBold, Joseph F, Miczek, Klaus A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200498/
https://ncbi.nlm.nih.gov/pubmed/24917195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.139
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