Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia

IMPORTANCE: With cure rates of childhood acute lymphoblastic leukemia (ALL) exceeding 85%, there is compelling need to mitigate treatment toxicities that can compromise quality of life. Peripheral neuropathy is the major dose-limiting toxicity of the microtubule inhibitor vincristine, an anticancer...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:JAMA
Autori principali: Diouf, Barthelemy, Crews, Kristine R., Lew, Glen, Pei, Deqing, Cheng, Cheng, Bao, Ju, Zheng, Jie J., Yang, Wenjian, Fan, Yiping, Wheeler, Heather E., Wing, Claudia, Delaney, Shannon M., Komatsu, Masaaki, Paugh, Steven W., McCorkle, Joseph Robert, Lu, Xiaomin, Winick, Naomi J., Carroll, William L., Loh, Mignon L., Hunger, Stephen P., Devidas, Meenakshi, Pui, Ching-Hon, Dolan, M. Eileen, Relling, Mary V., Evans, William E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377066/
https://ncbi.nlm.nih.gov/pubmed/25710658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2015.0894
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi