α7 Nicotinic Acetylcholine Receptor-Specific Antibody Induces Inflammation and Amyloid β(42) Accumulation in the Mouse Brain to Impair Memory

Nicotinic acetylcholine receptors (nAChRs) expressed in the brain are involved in regulating cognitive functions, as well as inflammatory reactions. Their density is decreased upon Alzheimer disease accompanied by accumulation of β-amyloid (Aβ(42)), memory deficit and neuroinflammation. Previously w...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Lykhmus, Olena, Voytenko, Larysa, Koval, Lyudmyla, Mykhalskiy, Sergiy, Kholin, Victor, Peschana, Kateryna, Zouridakis, Marios, Tzartos, Socrates, Komisarenko, Sergiy, Skok, Maryna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376778/
https://ncbi.nlm.nih.gov/pubmed/25816313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122706
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