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α7 Nicotinic Acetylcholine Receptor-Specific Antibody Induces Inflammation and Amyloid β(42) Accumulation in the Mouse Brain to Impair Memory
Nicotinic acetylcholine receptors (nAChRs) expressed in the brain are involved in regulating cognitive functions, as well as inflammatory reactions. Their density is decreased upon Alzheimer disease accompanied by accumulation of β-amyloid (Aβ(42)), memory deficit and neuroinflammation. Previously w...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376778/ https://ncbi.nlm.nih.gov/pubmed/25816313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122706 |
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