α7 Nicotinic Acetylcholine Receptor-Specific Antibody Induces Inflammation and Amyloid β(42) Accumulation in the Mouse Brain to Impair Memory

Nicotinic acetylcholine receptors (nAChRs) expressed in the brain are involved in regulating cognitive functions, as well as inflammatory reactions. Their density is decreased upon Alzheimer disease accompanied by accumulation of β-amyloid (Aβ(42)), memory deficit and neuroinflammation. Previously w...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Lykhmus, Olena, Voytenko, Larysa, Koval, Lyudmyla, Mykhalskiy, Sergiy, Kholin, Victor, Peschana, Kateryna, Zouridakis, Marios, Tzartos, Socrates, Komisarenko, Sergiy, Skok, Maryna
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376778/
https://ncbi.nlm.nih.gov/pubmed/25816313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122706
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