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An Essential Signal Peptide Peptidase Identified in an RNAi Screen of Serine Peptidases of Trypanosoma brucei

The serine peptidases of Trypanosoma brucei have been viewed as potential drug targets. In particular, the S9 prolyl oligopeptidase subfamily is thought to be a good avenue for drug discovery. This is based on the finding that some S9 peptidases are secreted and active in the mammalian bloodstream,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Moss, Catherine X., Brown, Elaine, Hamilton, Alana, Van der Veken, Pieter, Augustyns, Koen, Mottram, Jeremy C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376731/
https://ncbi.nlm.nih.gov/pubmed/25816352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123241
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