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Trypanosoma brucei Metacaspase 4 Is a Pseudopeptidase and a Virulence Factor
Metacaspases are caspase family cysteine peptidases found in plants, fungi, and protozoa but not mammals. Trypanosoma brucei is unusual in having five metacaspases (MCA1–MCA5), of which MCA1 and MCA4 have active site substitutions, making them possible non-enzymatic homologues. Here we demonstrate t...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220528/ https://ncbi.nlm.nih.gov/pubmed/21949125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.292334 |
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