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Neuronal aggregates: formation, clearance and spreading
Proteostasis is maintained by multiple cellular pathways, including protein synthesis, quality control and degradation. An imbalance of neuronal proteostasis, associated with protein misfolding and aggregation, leads to proteinopathies or neurodegeneration. While genetic variations and protein modif...
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| Veröffentlicht in: | Dev Cell |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376477/ https://ncbi.nlm.nih.gov/pubmed/25710535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.02.002 |
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