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Neuronal aggregates: formation, clearance and spreading

Proteostasis is maintained by multiple cellular pathways, including protein synthesis, quality control and degradation. An imbalance of neuronal proteostasis, associated with protein misfolding and aggregation, leads to proteinopathies or neurodegeneration. While genetic variations and protein modif...

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Bibliografiske detaljer
Udgivet i:Dev Cell
Main Authors: Lim, Junghyun, Yue, Zhenyu
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376477/
https://ncbi.nlm.nih.gov/pubmed/25710535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.02.002
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