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Transmission electron microscopy as an orthogonal method to characterize protein aggregates
Aggregation of protein-based therapeutics is a challenging problem in the biopharmaceutical industry. Of particular concern are implications for product efficacy and clinical safety due to potentially increased immunogenicity of the aggregates. We used transmission electron microscopy (TEM) to chara...
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| Publié dans: | J Pharm Sci |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376473/ https://ncbi.nlm.nih.gov/pubmed/25231267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24157 |
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